4 Dr. PI BranemarkOsseointegration is the direct structural and functional connection between living bone and the surface of a load-bearing implant, typically made of titanium, Ora direct bone-to-implant contact and later on defined on a more functional basis as a direct bone-to-implant contact under load
8 鈦金屬與組織之界面The surface TiO2 layer is extremely inert to corrosion. The Ti-peroxy compound that forms on this layer deactivates inflammatory cells, and enhancing the biocompatibility of pure titanium and the establishment of osseointegration.
14 表面粗糙度之生物影響 Macro-sized topology: 10 μm ~ mm Directly related to implant geometry-Threaded screw, macroporous surface treatmentRisk of increase in peri-implantitis & ionic leakage- Moderate roughness: 1~2 μmMicro-sized topology: 1~10 μmMaximizing bone-implant interlocking- Greater bone-to-implant contact (BIC)- Higher resistance of torque removalIdeal surface: hemispherical pits 1.5 μm in depth & 4 μm in diameterNano-sized topology: nmAdsorption of proteins & adhesion of osteoblastsReproducible surface roughness of nm range is difficult toproduce with chemical treatmentsLe Gu’ehennec et al., Surface treatments of titanium dental implants for rapid osseointegration,dental materials, 2007
15 人工牙根表面處理與粗糙度Le Gu’ehennec et al., Surface treatments of titanium dental implants for rapid osseointegration,dental materials, 2007