普萘洛尔 Ver. 2.0
手性的影响 血浆蛋白结合率 肝脏选择性代谢
血浆蛋白结合率 1.α1酸性糖蛋白 2. 竞争性取代
肝脏选择性代谢
旧药新应用 前景:对血管生长的抑制作用 经由CD147介导的血管内皮细胞凋亡
CD147 跨膜糖蛋白 血管内皮生长因子表达增高
对照组 实验组
参考文献 The Effect of Propranolol on Aortic Structure and Function in Normotensive RatsKonstantinos M. LaMpropouLos,* DiMitriosp. soKoLis,* Constantinosa. DiMitriou, MiChaLis KatsiMpouLas, EvangELos BaLafas, anna agapaKi, panayotis E. KarayannaCos, harisios BouDouLas Transport Model Of Drug In Vitro and the Study of Transport Kinetics of Propranolol Enantiomers Xia Xu Stereoselectivity Analysis of Propranolol Enantiomer and Study Function of GBLP Xiaoqin Mao Mechanism of propranolol-·induced apoptosis in human umbilical vein endothelial cells Wolong Xie
谢谢!