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Kazusa DNA Research Institute 見學報告

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Presentation on theme: "Kazusa DNA Research Institute 見學報告"— Presentation transcript:

1 Kazusa DNA Research Institute 見學報告
2001/10/12 KDRI 鳥瞰圖 (來源:Kazusa Akademia Park)

2 Kazusa DNA Research Institute 特點:
(1) 千葉縣政府獨立支持 (2) 專注在 DNA 的研究 重要歷程: 1991 開所計畫研議完成 1994 研究所建設完成開張 1996 完成藍綠細菌基因體定序 2000 共同完成阿拉伯芥基因體定序

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4 後基因體時代的策略: cDNA Large protein Polygenic diseases 全長的 cDNA 將是所有目光的焦點
會導致病變的基因都相當大 Polygenic diseases 許多疾病並非由單一基因所導致 鎖定三個重點 KDRI 所長大石道夫

5 Brain cell total poly(A)+ RNA
RT-PCR cDNA Electrophoresis cDNA > 4 kb pBluescript cDNA bank Electroporation Transformants 8,000,000

6 HUGE A Database of Human Unidentified Gene-Encoded Large Proteins Protein > 50 kDa

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8 基因體定序 藍綠細菌 阿拉伯芥 1990~1995 1996~2000 2001~? cDNA-Large Protein HUGE


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