一般外科近五年(100-104) 學術研究及論文發表

常傳訓醫師 研究計畫 論文發表2-1 亞太區之乳癌調查 (2007-2014):賽諾菲藥廠 乳癌病患使用Oncotype-DX檢測作為額外治療決策工具之回溯性研究(2013) 乳癌病患合併家族史之基因體分析(2014) 共同主持人:陽明大學 王學偉教授 利用次世代定律研究家族性乳癌(2015) 共同主持人:陽明大學 王學偉教授 論文發表2-1 Toxicological evaluation of Antrodia cinnamomea in BALB/c mice. Chang JB, Wu MF, Lu HF, Chou J, Au MK, Liao NC, Chang CH, Huang YP, Wu CT, Chung JG. In Vivo. 2013 Nov-Dec;27(6):739-45. Oral administration of benzyl-isothiocyanate inhibits in vivo growth of subcutaneous xenograft tumors of human malignant melanoma A375.S2 cells. Ni WY, Hsiao YP, Hsu SC, Hsueh SC, Chang CH, Ji BC, Yang JS, Lu HF, Chung JG. In Vivo. 2013 Sep-Oct;27(5):623-6. p53 modulates the AMPK inhibitor compound C induced apoptosis in human skin cancer cells. Huang SW, Wu CY, Wang YT, Kao JK, Lin CC, Chang CC, Mu SW, Chen YY, Chiu HW, Chang CH, Liang SM, Chen YJ, Huang JL, Shieh JJ. Toxicol Appl Pharmacol. 2013 Feb 15;267(1):113-24. doi: 10.1016/j.taap.2012.12.016. Epub 2012 Dec 27. Extract of medicinal mushroom Agaricus blazei Murill enhances the non-specific and adaptive immune activities in BALB/c mice. Ni WY, Wu MF, Liao NC, Yeh MY, Lu HF, Hsueh SC, Liu JY, Huang YP, Chang CH, Chung JG. In Vivo. 2013 Nov-Dec;27(6):779-86.

常傳訓 論文發表2-2 以體外細胞染色體異常試驗評估巴西蘑菇食品安全性。 吳銘芳、李美慧、常傳訓、黃幸妮、敖曼冠、劉嘉又、薛樹清、廖年捷、呂旭峰＊)。 J Biomed Lab Sci 2012; 24: 132-137。 以微核試驗評估巴西蘑菇的食用安全性。 吳銘芳、常傳訓、吳龍源、敖立燕、敖曼冠、薛樹清＊、呂旭峰。 傳統醫學雜誌 2012; 23: 23-33。 薛樹清、常傳訓、呂汶紋、鍾明燈、廖年捷、劉嘉又、莊穎瑩、呂旭峰。以微核試驗評估巴西 蘑菇的食用安全性。 安泰醫護雜誌 2011; 17:1:1-14。 呂旭峰、莊穎瑩、吳龍源、常傳訓、敖曼冠。 傳統醫學雜誌 2011; 22:1:10-25。 台灣早期乳癌存活病患飲食生活型態。 常傳訓、 殷秀妙、 董道興、 張仙平。 臺灣醫學 2010; 14:3:241-249 以牛樟芝餵食小鼠28 天亞急性毒性試驗之組織病理與生化分析。 吳銘芳、 李美慧、 黃韶顏、 劉嘉又、 鍾明燈、 常傳訓、 敖曼冠、廖年捷、薛樹清、呂旭峰。 Journal of Biomedical & Laboratory Sciences 2011;24:1:7-13。

蘇正熙醫師 研究計畫 102年振陽研究計劃 從豬肝門靜脈注射人類臍帶間質幹細胞治療STZ誘導囊尿病豬之研究 蔡佩君, 陳天華, 蘇正熙 103年振陽研究計劃 人類臍帶間葉幹細胞在非肥胖型糖尿病小鼠體內免疫調控機轉之研究

論文發表--蘇正熙 99年度 Hung-Hsu Hung, De-Feng Huang, Cheng-Hwai Tzeng, Cheng-Hsi Su, Tung-Ping Su, Hung-Chieh Chen, Shyh-Haw Tsay, Han-Chieh Lin, Jaw-Ching Wu, Shou-Dong Lee and Chien-Wei Su Systemic Amyloidosis Manifesting as a Rare Cause of Hepatic Failure J Chin Med Assoc. 2010 Mar;73(3):161-5 SCI Fu-Jie Chuang, Jui-Yu Chen, Jia-Fwu Shyu, Cheng-Hsi Su, Yi-Ming Shyr, Chew-Wun Wu, Wing-Yui Lui, Chen-Shen Lee, Tien-Hua Chen. Surgical anatomy of the external branch of the superior laryngeal nerve in Chinese adults and its clinical applications. Head & Neck 2010;32(1): 53 -57. (SCI) 100年度 Shin-E Wang, Cheng-Hsi Su, Ying-Ju Kuo, Yi-Ming Shyr *, Anna Fen-Yau Li, Tien-Hua Chen, Chew-Wun Wu, and Chen-Hsen Lee, Comparison of Functional and Nonfunctional Neuroendocrine Tumors in the Pancreas and Peripancreatic Region Pancreas 2011;40: 253~259 (SCI) Jung-Sheng Chien , Pei-Jiun Tsai , Kuang-Yi Liu , Shin-E Wang , Yi-Ming Shyr , Cheng-Hsi Su, and Tien-Hua Chen . Open Suture Repair and Open Onlay Technique for Incisional Hernia in Elderly Patients with Multiple Comorbidities. International J of applied science and technology (IJAST) 2011; Vol. 1(3):34-40 Meng-Hsuan Chung, Shin-E Wang, Yi-Ming Shyr, Anna Fen-Yau Li, Tien-Hua Chen, Cheng-Hsi Su, Chew-Wun Wu. Pancreatic and Periampullary Mixed Tumors. Hepato-Gastroenterology 2011; Aug. (accepted)

論文發表--蘇正熙 101年度 Jui-Hsia Hung, Shin-E Wang, Yi-Ming Shyr *, Cheng-Hsi Su, Tien-Hua Chen, Chew-Wun Wu. Resection for Secondary Malignancy of the Pancreas. Pancreas 2012; 41(1):121-9 SCI Pei-Jiun Tsai, Kuang-Yi Liu , Shin-E Wang , Yi-Ming Shyr , Cheng-Hsi Su , and Tien-Hua Chen A Case of Solitary Neurofibroma of the Pancreas Body not Associated with Type 1 Neurofibromatosis. J Chin Med Assoc 2012;75(3):132-5. Pei-Jiun Tsai, Shin-E Wang, Yi-Ming Shyr*, Tien-Hua Chen, Cheng-Hsi Su and Chew-Wun Wu Diagnostic and Therapeutic Dilemmas in Periampullary Lesions Hepato-Gastroenterology 2012; 59:1621-1625 SCI Kuo-Chung Wang, Yi-Ming Shyr, Shin-E Wang, Cheng-Hsi Su, Tien-Hua Chen, Chew-Wun Wu. Reappraisal of pancreatic adenocarcinoma undergoing pancreaticoduodenectomy. Hepato-Gastroenterology 2012 Sep;59(118):1976-80 Shin-E Wang, Yi-Ming Shyr*, Cheng-Hsi Su, Tien-Hua Chen, Chew-Wun Wu, Palliative Pancreaticoduodenectomy in Pancreatic and Periampullary Adenocarcinomas. Pancreas 2012;41: 882~87

論文發表--蘇正熙 103年度 Man-Hsin Hung,Chun-Yu Liu, Cheng-Ying Shiau, Chin-Yi Hsu, Yi-Fang Tsai, Yu-Ling Wang, Ling-Chen Tai, Kuang-Liang King, Ta-Chung Chao, Jen-Hwey Chiu, Cheng-Hsi Su, Su-Shun Lo, Cheng-Hwai Tzeng, Yi-Ming Shyr. Effect of Age and Biological Subtype on the Risk and Timing of Brain Metastasis in Breast Cancer Patients. PLos One 2014;9(2): e89389 Tsai PJ, Wang HS, Lin GJ, Chou SC, Chu TH, Chuan WT, Lu YJ, Weng ZC, Su CH, Hsieh PS, Sytwu HK, Lin CH, Chen TH, Shyu JF. Undifferentiated Wharton’s Jelly Mesenchymal Stem Cell Transplantation Induces Insulin-Producing Cell Differentiation and Suppression of T Cell-Mediated Autoimmunity in Non-Obese Diabetic Mice. Cell Transplant. 2014 Jul 15. [Epub ahead of print]

劉孟綸醫師 研究計畫 2010-2012開發以術後廢棄脂肪組織培養出之人類成體間質幹細胞以應用於臨床治療策略 Development of Human Adult Mesenchymal Stem Cells derived from Surgical Operation Abandoned Adipose Tissue for Clinical Treatment Strategies陽明大學 房同經教授, 振興醫院 一般外科 劉孟綸主任 2012 Human Stem cell Based Tissue Engineering Strategy on Oral Mucosa Reconstruction 應用人類成體幹細胞發展口腔黏膜組織工程修復策略 計畫主持人:陽明大學 牙醫學系許明倫 教授, 振興醫院 一般外科 劉孟綸 主任

論文發表--劉孟綸 1. 後腹腔副神經瘤以顯影劑電腦斷層掃描後誘發心絞痛合併X症候群表現 劉孟綸 劉啟明 劉玉錫 何愛生* Retroperitoneal Paraganglioma Presents as Angina with Syndrome X after Contrast Enhanced Computerized Tomography Scan台灣外科醫學會 年會暨第69次學術 演講會 The 69th Annual Meeting of Taiwan Surgical Association 2010-3-22 Taipei LIPOLYSIS AND HEPATIC PROTECTIVE EFFECTS OF TRIMUCRIN IN SPRAGUE-DAWLEY RATS FED WITH HIGH FAT DIET, Meng-lun Liu ,Juin-Hong Cheng2, Kae-Shin Lin, Ai-Sheng Ho, Tong-Jing Fang; UEGW 2010 (United European Gastroenterology Week) Barcelona, Spain, 2010-10-18~25 2. 來源不明之後腹腔淋巴結轉移性神經內分泌癌 METASTATIC NEUROENDOCRINE CARCINOMA OF THE RETROPERITONEAL LYMPH NODE WITH UNDETECTABLE PRIMARY ORIGIN劉孟綸 劉啟明 劉玉錫 何愛生 台灣外科醫學會 年會暨第70次學術 演講會 The 70th Annual Meeting of Taiwan Surgical Association, 2011-3-19 Taipei 3. EARLY ADULT STEM CELLS HARVESTED EFFECTIVELY FROM ADIPOSE TISSUE OF DIGESTIVE SURGICAL PATIENTS; M.-L. Liu 1,*, J.-H. Cheng 2, K.-S. Lin 3, A.-S. Ho 4, T.-J. Fang 5, 1General Surgery, Cheng Hsin General Hospital, 2Institute of Clinical Dentistry, 3Pharmacology,National Yang-Ming University,4Gastroenterology, Cheng Hsin General Hospital, 5Internal Medicine, Songshan Armed Forces General Hospital, Taipei, Taiwan, China, UEGW (United European Gastroenterology Week) 2011, Stockholm, Sweden, 2011-10-12~26

論文發表--劉孟綸 4. Tracking the human adipose-derived stem cells in adult rats M.-L. Liu 1,* , J.-H. Cheng 2 , K.-S. Lin 3 , A.-S. Ho 4 , T.-J. Fang 5 1 General Surgery, Cheng Hsin General Hospital, 2 Institute of Clinical Dentistry, 3 Pharmacology, National Yang-Ming University, 4 Gastroenterology, Cheng Hsin General Hospital, 5 Internal Medicine, Songshan Armed Forces General Hospital, Taipei, Taiwan, China (APDW 2012 Dec. 5-8 Bangkok, Thailand) 5. APPLICATION OF HUMAN ADULT STEM CELL BASED TISSUE ENGINEERING STRATEGY ON RECONSTRUCTION OF ORAL TISSUE M.-L. Liu 1,*, J.-H. Cherng 2, S.-J. Chang 3, M.-L. Hsu 4 1General Surgery, Cheng Hsin General Hospital, 2Dentistry, National Yang-Ming University, , 3Dentistry, National Yang-Ming University,, Taipei, 4Dentistry, National Yang-Ming University,, Taipei (R.O.C.), Taiwan, Republic of China (UEGW Oct. 12-16, 2013 Berlin, Germany) 6. Sclerosing Encapsulating Peritonitis In Patients On Long Term Peritoneal Dialysis: Meng-lun Liu, Chi-Ming Liu, Ai-Sheng Ho, Division of General Surgery, and Gastroenterology, Cheng Hsin General Hospital, (APDW, 22-25,Nov. 2014 Bali, Indonesia)

Journal發表--劉孟綸 1. Novel biomarkers predict liver fibrosis in hepatitis C patients: alpha 2 macroglobulin, vitamin D binding protein and Apo lipoprotein AI, Ho AS, Cheng CC; Lee SC; Liu ML; Lee JY; Wang WM; Wang CC. Journal of Biomedical Science 2010, 17:58 2. A population-based cohort study of symptomatic gallstone disease in diabetic patients Liu, C.-M., Hsu, C.-T., Li, C.-Y., Chen, C.-C., Liu, M.-L., Liu, J.-H. World Journal of Gastroenterology volume 18, issue 14, year 2012, pp. 1652 – 1659 3. "Collagen matrix boosts osteogenesis from dental tissue-derived stem cells," by Shu-Jen Chang ….Meng-lun Liu et al, Journal of Dental Research(JDR); 2015 In press, Manuscript ID JDR-15-0114.

劉啟明醫師 1.研究計畫: 統計18歲以下急性闌尾炎與成年人發生率的不同 2. 口頭論文報告: The Asian Symposium on Health Informatics and Nursing Education, August 6-8, 2015 Hiroshima, Japan 題目: Impact of Diabetes Mellitus on Cholecystectomy Rate: A Population-Based Follow-Up Study 3. Journal 發表: A. The Correlation between Cholecystectomy and Seasonal Impact in Taiwan Chinese Journal of Physiology 57(1): 48-56, 2014 B. A population-based cohort study of symptomatic gallstone disease in diabetic patients World J Gastroenterol 2012 April 14; 18(14): 1652-1659 C. Impact of diabetes on cholecystectomy rate: A population-based follow-up study 台灣外科醫學會雜誌 第48卷第5期(104年09/10月)刊出

郭禎明醫師 1. 研究計畫 (2010-2015) 無 2. 會議報告 (2010-2015) 3. Journal發表 (2010-2015) CASE REPORTS IN GASTROENTEROLOGY June 30, 2015 Manuscript No.: 201506005 Title: Mixed Adenoneuroendocrine (MANECs) carcinoma of stomach (in submission)

邱一洲醫師 1. 研究計畫 (2010-2015) 無 2. 會議報告 (2010-2015) 3. Journal發表 (Next)

邱一洲醫師論文發表題目: 101年 科別 作者 題目 科別 作者 題目 科別 作者 題目 102年 神經外科 邱一洲 一般外科 邱一洲 Isolation and identification of acanthamoeba species from tehrmal spring environments in southern Taiwan Occurrence of diarrheagenic Escherichia coligenes in raw water of water treatment plants Identification of the Naegleria Species in Natural Watersheds Used for Drinking and Recreational Purposes in Taiwan Molecular detection and comparison of Acanthamoeba genotypes in different functions of watersheds in Taiwan 102年 科別 作者 題目 神經外科 邱一洲 Identification and quantitative detection of Legionella spp. in various aquatic environments by real-time PCR assay 103年 科別 作者 題目 一般外科 邱一洲 Application of TaqMan qPCR for the detection and monitoring of Naegleria species in reservoirs used as a source for drinking water