libD3C: 一种免参数的、支持不平衡分类的二类分类器 Quan Zou (邹 权) (Ph.D.& Professor) Tianjin University zouquan@tju.edu.cn

libD3C≈libSVM libSVM的缺点 优化参数慢 处理不平衡的分类效果不好

Kernel function parameter tuning in libSVM

Ensemble learning: Make weak classifiers to strong one h1( ) h2() h3( ) h4( ) h5( ) h6() h7() Classification Result Combine to form the Final strong classifier

选择性集成 改善集成学习的预测效果 选择性集成学习算法 问题 提高集成学习的预测速度 降低存储需求 Classifier 1 Classifier n 5 5

基于聚类的方法 Parameters tuning C1 Out1 Out1 Out1 Out1 Out1 Out1 Out1 Out1 Cluster1 C2 Out2 Out2 Out2 Out2 Out2 Out2 Out2 Out2 C2 Out2 C2 Data KMeans Cluster2 C3 Out3 Out3 C3 Out3 C3 Out3 Out3 Out3 C3 Out3 Cluster3 C9 C9 C9 C9 Out9 Out9 C9 Out9 C9 Out9 C10 Out10 Out10 Out10 Out10

模拟退火优化参数 SA

Predicting in parallel

2018/5/14

Ensemble learning for Class Imbalance Problem

Strategy First, the negative set is divided randomly into several subsets equally. Every subset together with the positive set is a class balance training set. Then several different classifiers are selected and trained with these balance training sets. They will vote for the last prediction when facing new samples. The samples will be added to the next two classifiers’ training sets if they are misclassified. Reference 邹权, 郭茂祖, 刘扬, 王峻. 类别不平衡的分类方法及在生物信息学中的应用. 计算机研究与发展. 2010,47(8):1407-1414 X.-Y. Liu, J. Wu, and Z.-H. Zhou. Exploratory undersampling for class-imbalance learning. IEEE Transactions on Systems, Man, and Cybernetics - Part B: Cybernetics, 2009, 39(2): 539-550

http://lab.malab.cn/soft/LibD3C/ 2018/5/14

http://lab.malab.cn/soft/MRMD/ Quan Zou, et al. A Novel Features Ranking Metric with Application to Scalable Visual and Bioinformatics Data Classification. Neurocomputing. 2016, 173:346-354

ESI High Cited Paper 2018/5/14

Application in Bioinformatics DNA Binding proteins Li Song, Dapeng Li, Xiangxiang Zeng, Yunfeng Wu, Li Guo*, Quan Zou*. nDNA-prot: Identification of DNA-binding Proteins Based on Unbalanced Classification. BMC Bioinformatics. 2014, 15:298. ESI高引论文(HIGHLY CITED PAPER) Cytokines Quan Zou, et al. An Approach for Identifying Cytokines Based On a Novel Ensemble Classifier. BioMed Research International. 2013, 2013:686090 tRNA Quan Zou, et al. Improving tRNAscan-SE annotation results via ensemble classifiers. Molecular Informatics. 2015,34(11-12):761-770 miRNA Leyi Wei, Minghong Liao, Yue Gao, Rongrong Ji, Zengyou He*, Quan Zou*. Improved and Promising Identification of Human MicroRNAs by Incorporating a High-quality Negative Set. IEEE/ACM Transactions on Computational Biology and Bioinformatics. 2014, 11(1):192-201 ESI高引论文(HIGHLY CITED PAPER)

利用邹权副教授提出的集成学习方法 2018/5/14

Thanks ! http://lab.malab.cn/soft/LibD3C/ Quan Zou（PH.D., Prof.） School of Computer Sci &Tech@Tianjin Univ. Email：zouquan@nclab.net http://lab.malab.cn/ 2018/5/14