生物信息学 第三章 基因组学与序列分析 张高川 生物信息学教研室 (Department of Bioinformatics) 基础医学与生物科学学院 (School of Biology and Basic Medical Science) 苏州大学医学部 (Medical College of Soochow University) Email: zhanggaochuan@suda.edu.cn Tel: 15862330958 QQ: 2257916241
What is genome or genomics?
What is genome or genomics? Genome >> a haploid genome The term was adapted in 1920 by Hans Winkler (23 April 1877 – 22 November 1945) , professor of botany at the University of Hamburg, Germany. Nuclear /Chromosomal genome
What is genome or genomics? Genome >> a haploid genome The term was adapted in 1920 by Hans Winkler (23 April 1877 – 22 November 1945) , professor of botany at the University of Hamburg, Germany. Nuclear /Chromosomal genome
What is genome or genomics? Genome >> a haploid genome The term was adapted in 1920 by Hans Winkler (23 April 1877 – 22 November 1945) , professor of botany at the University of Hamburg, Germany. Nuclear /Chromosomal genome Mitochondrial genome
What is genome or genomics? Genome >> a haploid genome The term was adapted in 1920 by Hans Winkler (23 April 1877 – 22 November 1945) , professor of botany at the University of Hamburg, Germany. Nuclear /Chromosomal genome Mitochondrial genome
What is genome or genomics? Genome >> a haploid genome The term was adapted in 1920 by Hans Winkler (23 April 1877 – 22 November 1945) , professor of botany at the University of Hamburg, Germany. Nuclear /Chromosomal genome Mitochondrial genome Chloroplast genome
What is genome or genomics? Genome >> a haploid genome The term was adapted in 1920 by Hans Winkler (23 April 1877 – 22 November 1945) , professor of botany at the University of Hamburg, Germany. Nuclear /Chromosomal genome Mitochondrial genome Chloroplast genome
What is genome or genomics? Genome >> a haploid genome The term was adapted in 1920 by Hans Winkler (23 April 1877 – 22 November 1945) , professor of botany at the University of Hamburg, Germany. Nuclear /Chromosomal genome Mitochondrial genome Chloroplast genome
What is genome or genomics? Genome >> a haploid genome The term was adapted in 1920 by Hans Winkler (23 April 1877 – 22 November 1945) , professor of botany at the University of Hamburg, Germany. Nuclear /Chromosomal genome Mitochondrial genome Chloroplast genome Virus genome
What is genome or genomics? Genome >> a haploid genome The term was adapted in 1920 by Hans Winkler (23 April 1877 – 22 November 1945) , professor of botany at the University of Hamburg, Germany. Nuclear /Chromosomal genome Mitochondrial genome Chloroplast genome Virus genome
What is genome or genomics? Genome >> a haploid genome The term was adapted in 1920 by Hans Winkler (23 April 1877 – 22 November 1945) , professor of botany at the University of Hamburg, Germany. Nuclear /Chromosomal genome Mitochondrial genome Chloroplast genome Virus genome The term genomics was coined in 1987 by Victor A. McKusick and Frank H. Ruddle as the title for a new journal of that name. Genomics Genomics is a discipline in genetics that applies recombinant DNA, DNA sequencing methods, and bioinformatics to sequence, assemble, and analyze the function and structure of genomes.
(Human Genome Project, HGP) National Institutes of Health (NIH) 现代生命科学研究的一个大事件 人类基因组计划 (Human Genome Project, HGP) (30亿个碱基对) National Institutes of Health (NIH) 美国能源部人类基因组计划徽标 1990-2005； 30亿美元 英国、日本、法国、德国、中国、印度 1998 美国科学家克莱格·凡特 塞雷拉基因组公司 (Celera Genomics) 2000.6.26, 克林顿 国际人类基因组组织（HUGO） 1998 1999年9月，中国正式加入HGP； 人类第3号染色体的短臂区域3000万个碱基对（1％）。 1999
(Human Genome Project, HGP) 人类基因组计划 (Human Genome Project, HGP) 30亿个碱基对 ? 数学方法 计算机技术 基因组注释 新基因发现 接下来，该怎么办？ 基因组比较
NCBI >> Genbank 选择Genome数据库, 空搜索直接进入
NCBI >> Genbank >> Genome 按物种类别浏览基因组数据库
NCBI >> Genbank >> Genome >> Browse by Organism
NCBI >> Genbank >> Genome 通过FTP方式下载基因组数据
NCBI >> Genbank >> Genome >> Download by FTP
NCBI >> Genbank >> Genome >> Download by FTP
NCBI >> Genbank >> Genome >> Download by FTP >> H_sapiens (人类)
NCBI >> Genbank >> Genome >> Download by FTP >> H_sapiens (人类) >> CHR_01
NCBI >> Genbank >> Genome >> Download by FTP (FileZilla)
NCBI >> Genbank >> Genome >> Download by FTP (FileZilla)
NCBI >> Genbank >> Genome >> Download by FTP (FileZilla)
NCBI >> Genbank >> Genome >> Download by FTP (FileZilla) >> CHR_Un
NCBI >> Genbank >> Genome >> Download by FTP (FileZilla) >> GFF
NCBI >> Genbank >> Genome 人类基因组资源
NCBI >> Genbank >> Genome >> 人类基因组资源
NCBI >> Genbank >> Gene >> TP53搜索结果
NCBI >> Genbank >> Gene >> TP53
NCBI >> Genbank >> Gene >> TP53
NCBI >> Genbank >> Gene >> TP53 >> Map Viewer
TNCBI >> Genbank >> Gene >> TP53 >> Map Viewer >> 负链编码基因 S
TNCBI >> Genbank >> Gene >> TP53 >> Map Viewer >> 负链编码基因 S
TNCBI >> Genbank >> Gene >> TP53 >> Map Viewer >> 下载序列
Genome和Genomics相关文献资料查阅 Genbank数据库之Genome子库使用练习 拓展阅读和实践练习 Genome和Genomics相关文献资料查阅 Genbank数据库之Genome子库使用练习
TNCBI >> Genbank >> Gene >> TP53 >> Map Viewer >> 下载序列 >> FASTA格式
Genome和Genomics相关文献资料查阅 Genbank数据库之Genome子库使用练习 拓展阅读和实践练习 Genome和Genomics相关文献资料查阅 Genbank数据库之Genome子库使用练习
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